BDBM309408 (2R,3aS,4R,9bS)-N-benzyl-12- (cyclopropylmethyl)-3a,8-dihydroxy- 1,2,3,3a,4,5-hexahydro-4,9b- (epiminoethano)cyclopenta[a]naphthalene- 2-carboxamide::US9656962, Compound 33

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@H](C[C@@]34O)C(=O)NCc3ccccc3)c2c1

InChI Key InChIKey=UOCAMDNZRYYWSM-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 309408   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309408(US9656962, Compound 33 | (2R,3aS,4R,9bS)-N-benzyl-...)
Affinity DataKi:  0.75nMAssay Description:Radioligand binding assays (screening and dose-displacement) use 0.1 nM [3H]-nociceptin (Perkin Elmer, Shelton, Conn.; 87.7 Ci/mmole) with 12 μg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309408(US9656962, Compound 33 | (2R,3aS,4R,9bS)-N-benzyl-...)
Affinity DataKi:  1.39nMAssay Description:δ-Opioid Receptor Binding Assay Procedures: δ-Opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309408(US9656962, Compound 33 | (2R,3aS,4R,9bS)-N-benzyl-...)
Affinity DataEC50:  7.03nMAssay Description:Radioligand binding assays (screening and dose-displacement) use 0.1 nM [3H]-nociceptin (Perkin Elmer, Shelton, Conn.; 87.7 Ci/mmole) with 12 μg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309408(US9656962, Compound 33 | (2R,3aS,4R,9bS)-N-benzyl-...)
Affinity DataEC50: >2.00E+4nMAssay Description:δ-Opioid Receptor Binding Assay Procedures: δ-Opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent