BDBM309418 (2R,3aS,4R,9bS)-2-amino-12- (cyclopropylmethyl)-1,2,3,3a,4,5- hexahydro-4,9b-(epiminoethano)- cyclopenta[a]naphthalene-3a,8-diol::US9656962, Compound 22

SMILES N[C@H]1C[C@@]2(O)[C@H]3Cc4ccc(O)cc4[C@]2(C1)CCN3CC1CC1

InChI Key InChIKey=CRKOKOFIUAFPPC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309418   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309418(US9656962, Compound 22 | (2R,3aS,4R,9bS)-2-amino-1...)
Affinity DataEC50:  25.7nMAssay Description:Radioligand binding assays (screening and dose-displacement) use 0.1 nM [3H]-nociceptin (Perkin Elmer, Shelton, Conn.; 87.7 Ci/mmole) with 12 μg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309418(US9656962, Compound 22 | (2R,3aS,4R,9bS)-2-amino-1...)
Affinity DataEC50: >2.00E+4nMAssay Description:δ-Opioid Receptor Binding Assay Procedures: δ-Opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent