BDBM3099 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 66::6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]-phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, N-Oxide::6-(2,6-dichlorophenyl)-2-({4-[2-(diethyloxo--azanyl)ethoxy]phenyl}amino)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog

SMILES CC[N+]([O-])(CC)CCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1

InChI Key InChIKey=DLGVUWDAFXDBEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3099   

TargetFibroblast growth factor receptor 1(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3099(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 66 | 6-(2,...)
Affinity DataIC50:  46nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3099(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 66 | 6-(2,...)
Affinity DataIC50:  120nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed