BDBM3105 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72::4-(4-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-2-yl]amino}phenyl)butanoic acid::CHEMBL113070::PD 166285 analog

SMILES Cn1c2nc(Nc3ccc(CCCC(O)=O)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key InChIKey=CBIJGNHFFWAGLZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 3105   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3105(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72 | 4-(4-...)
Affinity DataIC50:  120nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3105(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72 | 4-(4-...)
Affinity DataIC50:  110nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3105(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72 | 4-(4-...)
Affinity DataIC50:  32nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3105(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72 | 4-(4-...)
Affinity DataIC50:  32nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM3105(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72 | 4-(4-...)
Affinity DataIC50:  32nMAssay Description:Inhibition of checkpoint kinase Wee1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM3105(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72 | 4-(4-...)
Affinity DataIC50:  32nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3105(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72 | 4-(4-...)
Affinity DataIC50:  80nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed