BDBM31091 PAZOPANIB

SMILES Cc4ccc(Nc3nccc(N(C)c2ccc1c(C)n(C)nc1c2)n3)cc4S(N)(=O)=O

InChI Key InChIKey=CUIHSIWYWATEQL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31091   

TargetCarbonic anhydrase 12(Human)
Tanta University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31091BDBM31091(PAZOPANIB)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human CA12 assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Tanta University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31091BDBM31091(PAZOPANIB)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human CA9 assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Tanta University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31091BDBM31091(PAZOPANIB)
Affinity DataKi:  12nMAssay Description:Inhibition of human CA1 assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Tanta University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31091BDBM31091(PAZOPANIB)
Affinity DataKi:  32nMAssay Description:Inhibition of human CA2 assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed