BDBM311048 US10155727, Example 103::USRE49517, Example 103

SMILES FC(F)c1cc(ccc1F)-c1cnn(Cc2cc(Cn3ccc(n3)-c3ccc(F)c(c3)C(F)F)n[nH]2)c1

InChI Key InChIKey=BGEGEEMDZPHRBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311048   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM311048(US10155727, Example 103 | USRE49517, Example 103)
Affinity DataIC50: 1.00E+3nMAssay Description:After thawing on the day of the assay, the membrane suspension was diluted further with 20 mM HEPES/0.1 mM KCl/pH 7.2.The incubation mixture of 200 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM311048(US10155727, Example 103 | USRE49517, Example 103)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding was terminated by filtration of the incubated membrane preparations using Filtermat B (Pharmacia, Uppsala Sweden) and a Micro Cell Harvester ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent