BDBM311140 example 6.60 on page 587 of WO15017610
SMILES C[C@@H](Oc1cc(cn2nc(C)cc12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1
InChI Key InChIKey=HSUHRICJWIVFQN-HUUCEWRRSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 311140
TargetTyrosine-protein kinase SYK [342-635](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 10.3nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3 [564-960](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 6.68E+3nMAssay Description:Recombinant human FLT3 (amino acids 564-958, Molecular weight 48.6 kDa, Invitrogen #PR4666C) was expressed with an Histidine tag. The test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Recombinant human Aurora B (amino acids 1-344, clone number DU1773, Molecular weight 40.2 kDa, University of Dundee) was expressed as a fusion protei...More data for this Ligand-Target Pair