BDBM311144 (S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(4-((7-fluoro-1- methyl-1H-indazol-4- yl)oxy)phenyl)pyrimidine-4- carboxamide::US10155752, Compound 24::US9834543, Compound 24

SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)c3n(C)ncc23)cc1)C(N)=O)C(N)=O

InChI Key InChIKey=RAWUCHYNMJXRKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311144   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM311144(US10155752, Compound 24 | (S)-6-((1-amino-1-oxopro...)
Affinity DataIC50: 601nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM311144(US10155752, Compound 24 | (S)-6-((1-amino-1-oxopro...)
Affinity DataIC50: 601nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent