BDBM311472 CHEM-US-00174::US10155764, Example 54::US10155764, Example 54A

SMILES CN(C)[C@H]1CCCC[C@H]1Nc1nn(C)c(=O)c2ccccc12

InChI Key InChIKey=BJZUGHOEXNZOQY-CABCVRRESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311472   

TargetHistone acetyltransferase KAT2B [719-832](Human)
Genentech

US Patent
LigandPNGBDBM311472(CHEM-US-00174 | US10155764, Example 54 | US1015576...)
Affinity DataIC50:  45nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone acetyltransferase KAT2B [719-832](Human)
Genentech

US Patent
LigandPNGBDBM311472(CHEM-US-00174 | US10155764, Example 54 | US1015576...)
Affinity DataIC50:  110nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent