BDBM31159 3-hydroxyquinolin-2(1H)-one, 13

SMILES Cc1ccc2[nH]c(=O)c(O)cc2c1

InChI Key InChIKey=HHBIREFHPDVOQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31159   

TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM31159(3-hydroxyquinolin-2(1H)-one, 13)
Affinity DataKi:  1.41E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31159(3-hydroxyquinolin-2(1H)-one, 13)
Affinity DataIC50: 2.75E+3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
North-West University

Curated by ChEMBL
LigandPNGBDBM31159(3-hydroxyquinolin-2(1H)-one, 13)
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed