BDBM311772 8-(7-Methyl-1H-indazol-5-yl)-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine-7-carbonitrile::US10155769, Example 10

SMILES Cc1cc(-c2c(C#N)ccn3nc(C(F)(F)F)nc23)cc2cn[nH]c12

InChI Key InChIKey=WKEMSMWQAOLEPU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311772   

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 311772BDBM311772(US10155769, Example 10 | 8-(7-Methyl-1H-indazol-5-...)
Affinity DataIC50: 20nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent