BDBM311913 N-[(2R)-1-[4-(4-methyl-1H-imidazol-5-yl)-1,4'-bipiperidin-1'-yl]-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide::US10166226, Example 2

SMILES Cc1nc[nH]c1C1CCN(C2CCN(C(=O)[C@@H](Cc3cc(C)c4[nH]ncc4c3)NC(=O)N3CCC(c4cc5ccccc5[nH]c4=O)CC3)CC2)CC1

InChI Key InChIKey=KLENFGVWYLLZFQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311913   

TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 311913BDBM311913(US10166226, Example 2 | N-[(2R)-1-[4-(4-methyl-1H-...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent