BDBM312079 3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-5- carbonitrile::US9603836, Compound 14

SMILES [C-]#[N+]c1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1

InChI Key InChIKey=ZGNZUDNGNWWUEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312079   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 312079BDBM312079(US9603836, Compound 14 | 3-(2,5-dioxopyrrolidin- 3...)
Affinity DataIC50: 1.20E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent