BDBM312268 3-(3-Pyrimidin-2-yl-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl)-bicyclo[2.2.2]oct-2-ene-2-carboxylic acid::US9604977, Example 19

SMILES OC(=O)C1=C(C2CCC1CC2)C(=O)Nc1sc2CCCCc2c1-c1ncccn1

InChI Key InChIKey=FNHLFAFACQNZHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312268   

TargetFatty acid-binding protein, adipocyte(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 312268BDBM312268(US9604977, Example 19 | 3-(3-Pyrimidin-2-yl-4,5,6,...)
Affinity DataIC50: 5.88E+3nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 312268BDBM312268(US9604977, Example 19 | 3-(3-Pyrimidin-2-yl-4,5,6,...)
Affinity DataIC50: 1.62E+4nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent