BDBM312402 2-[6,6-Difluoro-3-(3-trifluoromethyl-[1,2,4]oxadiazol-5-yl)-4,5,6,7-tetrahydro-benzo[b]-thiophen-2-ylcarbamoyl]-cyclohex-1-enecarboxylic acid::US9604977, Example 148::US9604977, Example 149

SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(no1)C(F)(F)F

InChI Key InChIKey=AEJMCKQMGAQIDR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 312402   

TargetFatty acid-binding protein, adipocyte(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 312402BDBM312402(US9604977, Example 149 | 2-[6,6-Difluoro-3-(3-trif...)
Affinity DataIC50: 40nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 312402BDBM312402(US9604977, Example 149 | 2-[6,6-Difluoro-3-(3-trif...)
Affinity DataIC50: 50nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 312402BDBM312402(US9604977, Example 149 | 2-[6,6-Difluoro-3-(3-trif...)
Affinity DataIC50: 8.49E+3nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 312402BDBM312402(US9604977, Example 149 | 2-[6,6-Difluoro-3-(3-trif...)
Affinity DataIC50: 1.27E+4nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent