BDBM313223 N-[3-[[2-[4-(4-ethylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide ::US10167264, Compound 10

SMILES CCN1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c(OC)c1

InChI Key InChIKey=OLFOXANEZJUWSR-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313223   

TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Jiangsu Medolution

US Patent
LigandPNGBDBM313223(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)-2-methoxy-anil...)
Affinity DataKd:  0.280nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent