BDBM313387 2-(difluoromethyl)-N- (3-(2-(3- (fluoromethyl)oxetan-3- yl)-6-(2- hydroxyethoxy)pyridin- 4-yl)-4- methylphenyl)isonicotin- amide::US10167279, Example 55

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)F)cc1-c1cc(OCCO)nc(c1)C1(CF)COC1

InChI Key InChIKey=DJQBPSLTIVOVQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313387   

LigandPNGBDBM313387(2-(difluoromethyl)-N- (3-(2-(3- (fluoromethyl)oxet...)
Affinity DataIC50: 74.7nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent