BDBM313736 5-{[2-{4-[5-Chloro-2-(difluoromethyl)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}-3-(pyridin-2-yl)propanoyl]amino}pyridine-2-carboxamide (racemate)::US10167280, Example 41

SMILES COc1cn(C(Cc2ccccn2)C(=O)Nc2ccc(nc2)C(N)=O)c(=O)cc1-c1cc(Cl)ccc1C(F)F

InChI Key InChIKey=GTGKMOIGBAOUJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313736   

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 313736BDBM313736(US10167280, Example 41 | 5-{[2-{4-[5-Chloro-2-(dif...)
Affinity DataIC50: 40nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 313736BDBM313736(US10167280, Example 41 | 5-{[2-{4-[5-Chloro-2-(dif...)
Affinity DataIC50: 62nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent