BDBM313806 US10167292, Example 50
SMILES Cc1nnn2CCN(c3ccc(Cl)cc3)c3cc(ccc3-c12)C(O)C(F)(F)F
InChI Key InChIKey=IENHPOBVKKOOQK-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 313806
Affinity DataIC50: 550nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
Catalyst Therapeutics
US Patent
Catalyst Therapeutics
US Patent
Affinity DataIC50: 550nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 204nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Catalyst Therapeutics
US Patent
Catalyst Therapeutics
US Patent
Affinity DataIC50: <100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair