BDBM31459 CHEMBL224485::substituted biphenyl derivative, 21
SMILES CC(C)CNC(=O)c1ccc(c(c1)C(O)=O)-c1ccccc1C(=O)Nc1ccc(cc1)C(N)=N
InChI Key InChIKey=OPEFANHGJWQXDF-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 31459
Affinity DataIC50: 120nMpH: 7.2 T: 23°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMT: 25°CAssay Description:Trypsin assay reactions were performed in a mixture containing trypsin, and test compounds were added at varied concentrations. The reactions were in...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+4nMT: 25°CAssay Description:Thrombin assay reactions were performed in a reaction mixture containing thrombin, and test compounds were added at varied concentrations. The reacti...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of human Fxa by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+5nMT: 25°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair