BDBM315278 5-(4-Bromophenyl)-3-[1-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]methyl]-4-piperidyl]-1H-imidazol-2-one::US10172843, Example 12

SMILES Cc1nc(-c2ccc(C(F)(F)F)cc2)[nH]c1CN1CCC(n2cc(-c3ccc(Br)cc3)[nH]c2=O)CC1

InChI Key InChIKey=SLAFMJIWACAPFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315278   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 315278BDBM315278(US10172843, Example 12 | 5-(4-Bromophenyl)-3-[1-[[...)
Affinity DataIC50: 590nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
US Patent