BDBM315343 3-{1-[5-Methyl-2-(4- trifluoromethanesulfonyl- phenyl)-1H-imidazol-4- ylmethyl]-piperidin-4- yl}-1H-pyrrolo[3,2- c]pyridine::US10172843, Example 77

SMILES Cc1[nH]c(-c2ccc(S(=O)(=O)C(F)(F)F)cc2)nc1CN1CCC(c2c[nH]c3ccncc23)CC1

InChI Key InChIKey=XBNPSQAUTIABIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315343   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 315343BDBM315343(US10172843, Example 77 | 3-{1-[5-Methyl-2-(4- trif...)
Affinity DataIC50: 155nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent