BDBM315924 2-[2,4-Difluoro-5-(7- morphoin-4-yl- quinazolin-4-yl)- phenyl]-2-pyrrolo- [1,2-a]pyrazin-1-yl- acetamide1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.23-8.19 (m, 1H), 7.93 (s, 1H), 7.80 (t,J = 8.2, 1H), 7.77 (dd, J = 2.4, 1.4, 1H), 7.63 (dd,J = 9.4, 3.1, 1H), 7.55 (dd, J = 12.3, 2.8, 1H), 7.50(d, J = 10.0, 1H), 7.44 (d, J = 4.8, 1H), 7.33 (s, 1H),7.21 (d, J = 2.5, 1H), 6.94-6.89 (m, 2H), 5.75 (s,1H), 3.82-3.77 (m, 4H), 3.49-3.45 (m, 4H).::US10172859, Example 348

SMILES NC(=O)C(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncn2cccc12

InChI Key InChIKey=QFPCISYAPZHVQS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 315924   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM315924(2-[2,4-Difluoro-5-(7- morphoin-4-yl- quinazolin-4-...)
Affinity DataKi:  1.25E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM315924(2-[2,4-Difluoro-5-(7- morphoin-4-yl- quinazolin-4-...)
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent