BDBM315950 US10172859, Example 374::US11065253, Example 374::US9732094, Example 374::[2-Fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[3,2-d}- pyrimidin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.08 (s,1H), 9.02 (s, 1H), 8.59 (d, J = 2.2, 1H), 8.20 (dd,J = 7.0, 2.3, 1H), 7.92 (d, J = 9.4, 1H), 7.77 (ddd,J = 8.4, 5.0, 2.4, 1H), 7.57 (dd, J = 9.5, 2.6, 1H),7.37 (dd, J = 10.0, 8.5, 1H), 7.27 (d, J = 2.3, 1H),7.22 (d, J = 2.5, 1H), 6.73 (d, J = 5.2, 1H), 6.48 (d,J = 5.1, 1H), 3.82-3.76 (m, 4H), 3.49-3.44 (m,4H).
SMILES OC(c1cc(ccc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1ncnc2ccoc12
InChI Key InChIKey=AYUGGJOQLWWJHH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 315950
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair