BDBM316034 (S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-(3-methoxy- pyrazin-2-yl)- methanolsee racemate::US10172859, Example 456::US11065253, Example 456

SMILES COc1nccnc1[C@@H](O)c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1

InChI Key InChIKey=BWGYCECICQRZBD-QHCPKHFHSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 316034   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM316034((S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quin...)
Affinity DataKi:  1.25E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM316034((S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quin...)
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM316034((S)-[2-Chloro-4- fluoro-5-(7- morpholin-4-yl- quin...)
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent