BDBM316132 2-({3-[(4-{3-[2-(2-methoxyethoxy)ethyl]ureido}phenyl)ethynyl]-1H-indazol-6-yl}thio)-N-methylbenzamide ::US9617222, Compound 7

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1ccc(NC(=O)NCCOCCOC)cc1

InChI Key InChIKey=KJEGCVJUDLSNRG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316132   

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandPNGBDBM316132(2-({3-[(4-{3-[2-(2-methoxyethoxy)ethyl]ureido}phen...)
Affinity DataIC50: 3.40nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
Ligand InfoPC sidSimilars
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent