BDBM31644 tetrahydrobenzothiophene (THBT), 23

SMILES CC1(C)CCc2c(C1)sc(NC(=O)c1ccccc1[N+]([O-])=O)c2C(N)=O

InChI Key InChIKey=OMWFNWQNOYXWNV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31644   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Gsk

LigandBDBM31644(tetrahydrobenzothiophene (THBT), 23)Copy SMILESCopy InChI

Affinity DataIC50:  398nMpH: 7.5 T: 23°CAssay Description:Inhibition of PDE4 is measured using a luminescence-coupled assay system developed by Cambrex. This assay system couples the formation of AMP, derive...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gsk

LigandBDBM31644(tetrahydrobenzothiophene (THBT), 23)Copy SMILESCopy InChI

Affinity DataIC50:  50nMpH: 7.5 T: 23°CAssay Description:Inhibition of PDE4 is measured using a luminescence-coupled assay system developed by Cambrex. This assay system couples the formation of AMP, derive...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL