BDBM316860 (3- cyanophenyl) methyl N-[3-[3- (2- oxobutanoylamino) phenyl]-1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate::US9617260, Compound 19

SMILES CCC(=O)C(=O)Nc1cccc(-c2c[nH]c3ncc(NC(=O)OCc4cccc(C#N)c4)cc23)c1

InChI Key InChIKey=BFHKIHRYKRRVFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316860   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 316860BDBM316860(US9617260, Compound 19 | (3- cyanophenyl) methyl N...)
Affinity DataIC50: 114nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluoresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent