BDBM316862 US9617260, Compound 21::benzyl N-[3- [3-[(1- cyanocyclopro- panecarbonyl) amino]phenyl]- 1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate

SMILES N#CC1(C(=O)Nc2cccc(-c3c[nH]c4ncc(NC(=O)OCc5ccccc5)cc34)c2)CC1

InChI Key InChIKey=NOKGRZLSYPMDKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316862   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 316862BDBM316862(US9617260, Compound 21 | benzyl N-[3- [3-[(1- cyan...)
Affinity DataIC50: 287nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluoresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent