BDBM316874 US9617260, Compound 32::propan-2-yl N- [3-(1-prop-2- enoylpiperidin- 4-yl)-1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate

SMILES C=CC(=O)N1CCC(c2c[nH]c3ncc(NC(=O)OC(C)C)cc23)CC1

InChI Key InChIKey=ZANLIINCDFGGLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316874   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 316874BDBM316874(US9617260, Compound 32 | propan-2-yl N- [3-(1-prop...)
Affinity DataIC50: 27nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluoresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent