BDBM317145 3-Methyl-6-[(E)-2-(2-methyl-5-pyrrolidin-1-yl-2H-[1,2,4]triazol-3-yl)vinyl]-imidazo[1,2-b]pyridazine-2-carbonitrile::US9617271, 3
SMILES Cc1c(nc2ccc(\C=C\c3nc(nn3C)N3CCCC3)nn12)C#N
InChI Key InChIKey=QFXJFOOABPKRDJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 317145
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
