BDBM317162 4-Chloro-6,7-dimethyl-2-(2-(1-methyl-5-(pyrrolidin-1-yl)-1H-1,2,4-triazol-3-yl)ethyl)-imidazo[1,2-f][1,2,4]triazine::US9617271, 20
SMILES Cc1nc2c(Cl)nc(CCc3nc(N4CCCC4)n(C)n3)nn2c1C
InChI Key InChIKey=DIBCNSNFQHYOCJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 317162
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 11nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
