BDBM317168 (E)-8-Isopropoxy-2,3-dimethyl-6-(2-(1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl)vinyl)imidazo[1,2-b]pyridazine::US9617271, 26

SMILES CC(C)Oc1cc(\C=C\c2nc(nn2C)N2CCCC2)nn2c(C)c(C)nc12

InChI Key InChIKey=OTEPGCAMXOPDBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317168   

LigandPNGBDBM317168(US9617271, 26 | (E)-8-Isopropoxy-2,3-dimethyl-6-(2...)
Affinity DataIC50: 0.493nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent