BDBM317171 2,3-Dimethyl-6-((1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl)ethynyl)-8-(methylsulfonyl)imidazo[1,2-b]pyridazine::US9617271, 29

SMILES Cc1nc2c(cc(nn2c1C)C#Cc1nc(nn1C)N1CCCC1)S(C)(=O)=O

InChI Key InChIKey=HWXHZALJIPXSKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317171   

LigandPNGBDBM317171(US9617271, 29 | 2,3-Dimethyl-6-((1-methyl-3-(pyrro...)
Affinity DataIC50: 5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent