BDBM317193 7-Cyclobutyl-2,3-dimethyl-6-((1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl)ethynyl)imidazo[1,2-b]pyridazine::US9617271, 51

SMILES Cc1nc2cc(C3CCC3)c(nn2c1C)C#Cc1nc(nn1C)N1CCCC1

InChI Key InChIKey=RZXPXIQAVWWJPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317193   

LigandPNGBDBM317193(US9617271, 51 | 7-Cyclobutyl-2,3-dimethyl-6-((1-me...)
Affinity DataIC50: 0.600nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent