BDBM317213 3-Methyl-5-[2-(2-methyl-5-pyrrolidin-1-yl-1,2,4-triazol-3-yl)ethynyl]-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine::US9617271, 71

SMILES Cc1c(nn2ccc(nc12)C#Cc1nc(nn1C)N1CCCC1)C(F)(F)F

InChI Key InChIKey=DHPYPZQKOLUQGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317213   

LigandPNGBDBM317213(US9617271, 71 | 3-Methyl-5-[2-(2-methyl-5-pyrrolid...)
Affinity DataIC50: 8.70nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent