BDBM3174 Bisindolylmaleimide 11a::ROCHE screening, 56::[(2-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}ethyl)sulfanyl]methanimidamide

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCSC(N)=N)c3ccccc23)c2ccccc12

InChI Key InChIKey=OGEQEAYTMFZUQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3174   

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3174(Bisindolylmaleimide 11a | ROCHE screening, 56 | [(...)
Affinity DataIC50:  41nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase TBK1(Human)
Technical University of Dortmund

LigandPNGBDBM3174(Bisindolylmaleimide 11a | ROCHE screening, 56 | [(...)
Affinity DataIC50:  883nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM3174(Bisindolylmaleimide 11a | ROCHE screening, 56 | [(...)
Affinity DataIC50:  1.21E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed