BDBM318049 (S)-3-(2,2-diphenylacetyl)-1,2,3,4-tetrahydrobenzo[5,6][1,4]dioxino[2,3-f]isoquinoline-2-carboxylic ::US9624234, 9

SMILES OC(=O)[C@@H]1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)ccc1Oc3ccccc3Oc21

InChI Key InChIKey=UFZZQNOSFLXWCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318049   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318049(US9624234, 9 | (S)-3-(2,2-diphenylacetyl)-1,2,3,4...)
Affinity DataIC50: 159nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent