BDBM318742 (2S,4S)-4-(benzyloxy)-1-(2,2-diphenylacetyl)pyrrolidine-2-carboxylic acid::US10370388, Compound 2::US9624243, 2

SMILES OC(=O)[C@@H]1C[C@@H](CN1C(=O)C(c1ccccc1)c1ccccc1)OCc1ccccc1

InChI Key InChIKey=BFTWTVUNMXYGBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318742   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318742((2S,4S)-4-(benzyloxy)-1-(2,2-diphenylacetyl)pyrrol...)
Affinity DataIC50: 114nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318742((2S,4S)-4-(benzyloxy)-1-(2,2-diphenylacetyl)pyrrol...)
Affinity DataIC50: 114nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent