BDBM318763 (2S,4R)-4-(2-(benzyloxy)ethyl)-1-(2,2-diphenylacetyl)-pyrrolidine-2-carboxylic acid::US10370388, Compound 55::US9624243, 55

SMILES OC(=O)[C@@H]1C[C@H](CCOCc2ccccc2)CN1C(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=HOCFJOJMTFGJRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318763   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318763((2S,4R)-4-(2-(benzyloxy)ethyl)-1-(2,2-diphenylacet...)
Affinity DataIC50: 386nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318763((2S,4R)-4-(2-(benzyloxy)ethyl)-1-(2,2-diphenylacet...)
Affinity DataIC50: 386nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent