BDBM318795 (2S,4S)-1-(2,2-diphenylacetyl)-4-(4-phenylbutyl)-pyrrolidine-2-carboxylic acid::US10370388, Compound 106::US9624243, 106

SMILES OC(=O)[C@@H]1C[C@H](CCCCc2ccccc2)CN1C(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=AOXCIYMWJSEDFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318795   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318795( (2S,4S)-1-(2,2-diphenylacetyl)-4-(4-phenylbutyl)-...)
Affinity DataIC50: 426nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318795( (2S,4S)-1-(2,2-diphenylacetyl)-4-(4-phenylbutyl)-...)
Affinity DataIC50: 426nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent