BDBM31962 carbohydrazide derivative, 5e

SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc(cc2)-c2ccccc2)c(O)c1Br

InChI Key InChIKey=MCVUTQRJNVPFIL-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31962   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM31962(carbohydrazide derivative, 5e)Copy SMILESCopy InChI

Affinity DataEC50:  1.70E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Shanghai Institute of Materia Medica

LigandBDBM31962(carbohydrazide derivative, 5e)Copy SMILESCopy InChI

Affinity DataAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL