BDBM319666 2-[1-(6-fluoro-2,3-dihydro-1H-inden-1-yl)-1H- imidazol-4-yl]-4-[5-(trifluoromethyl)-1H-1,2,3- triazol-4-yl]pyridine::US10174003, Example 85::US9896436, Example 85

SMILES Fc1ccc2c(c1)C(n1cnc(-c3cc(-c4nn[nH]c4C(F)(F)F)ccn3)c1)CC2

InChI Key InChIKey=GUGUWBOCGPLYEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319666   

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 319666BDBM319666(2-[1-(6-fluoro-2,3-dihydro-1H-inden-1-yl)-1H- imid...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 319666BDBM319666(2-[1-(6-fluoro-2,3-dihydro-1H-inden-1-yl)-1H- imid...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 319666BDBM319666(2-[1-(6-fluoro-2,3-dihydro-1H-inden-1-yl)-1H- imid...)
Affinity DataIC50: 500nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent