BDBM32028 (4Z)-3-hydroxy-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-oxazol-3-ylidene]cyclohexa-2,5-dien-1-one::(4Z)-3-hydroxy-4-[4-(2-methyl-4-thiazolyl)-5-(trifluoromethyl)-3-isoxazolylidene]-1-cyclohexa-2,5-dienone::(4Z)-3-hydroxy-4-[4-(2-methylthiazol-4-yl)-5-(trifluoromethyl)-4-isoxazolin-3-ylidene]cyclohexa-2,5-dien-1-one::(4Z)-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-(trifluoromethyl)-1,2-oxazol-3-ylidene]-3-oxidanyl-cyclohexa-2,5-dien-1-one::CHEMBL456678::MLS000027726::SMR000037581::cid_5389077

SMILES Cc1nc(cs1)-c1c(noc1C(F)(F)F)-c1ccc(O)cc1O

InChI Key InChIKey=FYZLHMNCPBFJAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32028   

TargetHeat shock protein HSP 90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM32028((4Z)-3-hydroxy-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Hsp90More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32028((4Z)-3-hydroxy-4-[4-(2-methyl-1,3-thiazol-4-yl)-5-...)
Affinity DataIC50:  1.65E+4nMpH: 7.4 T: 23°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay