BDBM321 (2S,3S)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-[(2R,3R)-4-[(3aR,7aS)-6-(tert-butylcarbamoyl)-octahydrothieno[3,2-c]pyridin-5-yl]-3-hydroxy-1-(phenylsulfanyl)butan-2-yl]carbamate::Thienopyridine thienyl urethane deriv. 16::hydroxyethylamine isostere::hydroxyethylene isostere

SMILES [H][C@]12CCS[C@@]1([H])CC(N(C[C@@H](O)[C@H](CSc1ccccc1)NC(=O)O[C@H]1CCS(=O)(=O)[C@H]1C(C)C)C2)C(=O)NC(C)(C)C

InChI Key InChIKey=ZYXJGWBYPOHODT-KAFGCEBJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM321((2S,3S)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  0.950nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article