BDBM321280 N-[3-(benzylmethylamino)propyl]-4-methoxybenzamide::US10179761, Compound 3.1.29

SMILES COc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1

InChI Key InChIKey=DJEAVYPAPNVIRK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 321280   

TargetSigma non-opioid intracellular receptor 1(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM321280(N-[3-(benzylmethylamino)propyl]-4-methoxybenzamide...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H](+)-pentazocine from S1R in human Jurkat cell membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM321280(N-[3-(benzylmethylamino)propyl]-4-methoxybenzamide...)
Affinity DataKi:  37nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM321280(N-[3-(benzylmethylamino)propyl]-4-methoxybenzamide...)
Affinity DataKi: >1.00E+3nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM321280(N-[3-(benzylmethylamino)propyl]-4-methoxybenzamide...)
Affinity DataKi: >1.20E+3nMAssay Description:Displacement of [3H]-DTG from S2R in human Jurkat cell membranes after 1 hr in presence of (+)-pentazocine by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2020
Entry Details Article
PubMed