BDBM322061 (E)-1-(4-(1-(1H-1,2,3-Triazole-4-carbonyl)piperidin-4-yl)piperazin-1-yl)-3-(4-chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)prop-2-en-1-one::US10183025, Example 149::US9763957, Example 149
SMILES Cc1nnn(Cc2cc(Cl)ccc2\C=C\C(=O)N2CCN(CC2)C2CCN(CC2)C(=O)c2c[nH]nn2)n1
InChI Key InChIKey=QAROVEBXQASZMU-HWKANZROSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 322061
Affinity DataIC50: 4.90nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 4.90nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair