BDBM322068 (E)-N-(1-(3-(2-((5-Methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl) acryloyl) piperidin-4-yl)-6-(1H-1,2,3-triazol-5-yl)hexanamide::US10183025, Example 156::US9763957, Example 156

SMILES Cc1nnn(Cc2cc(ccc2\C=C\C(=O)N2CCC(CC2)NC(=O)CCCCCc2cnn[nH]2)C(F)(F)F)n1

InChI Key InChIKey=PLLQUCGZNRRAKH-CSKARUKUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322068   

TargetAtaxin-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM322068((E)-N-(1-(3-(2-((5-Methyl-2H-tetrazol-2-yl)methyl)...)
Affinity DataIC50:  5.30nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM322068((E)-N-(1-(3-(2-((5-Methyl-2H-tetrazol-2-yl)methyl)...)
Affinity DataIC50:  5.30nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent