BDBM322565 US10183940, Example 18

SMILES Cn1nc(c2ccccc12)C(C)(C)NC(=O)c1cccc2CNCCOc12

InChI Key InChIKey=KRGAYCPFSCFSOW-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 322565   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM322565(US10183940, Example 18)
Affinity DataKi:  39.5nMAssay Description:Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM322565(US10183940, Example 18)
Affinity DataKi:  7.82E+3nMAssay Description:Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM322565(US10183940, Example 18)
Affinity DataKi:  8.71E+3nMAssay Description:Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM322565(US10183940, Example 18)
Affinity DataKi:  9.63E+3nMAssay Description:Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM322565(US10183940, Example 18)
Affinity DataKi:  9.86E+3nMAssay Description:Method description for binding assays with human Somatostatin receptors by use of CHO cell membranes expressing recombinant human SSTR1 or human SSTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM322565(US10183940, Example 18)
Affinity DataEC50:  4.40nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent