BDBM323029 (1R,2R)-2-[4-(3-Methyl-1H-pyrazol-5- yl)benzoyl]-N-(1-methyl-5-sulfamoyl-1H- pyrazol-4-yl)cyclohexanecarboxamide::US10183947, Example 13::US10508119, Example 13::US11001589, Example 13::US11691978, Example 13

SMILES Cc1cc(-c2ccc(C(=O)[C@@H]3CCCC[C@H]3C(=O)Nc3cnn(C)c3S(N)(=O)=O)cc2)[nH]n1

InChI Key InChIKey=IVYACETTWFJKQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323029   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 323029BDBM323029(US10183947, Example 13 | (1R,2R)-2-[4-(3-Methyl-1H...)
Affinity DataIC50: 33nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent